Nattermannallee 1 D - 50829 Köln fon +49 . 221. 8887-210
fax +49 . 221.
8887-211 info@acbiotec.de
FeedBeads
FeedBeads are polymer particles
enabling the user to run fed-batch processes in shake
flasks or microtiter plates. The user can now apply an
additional screening routine (batch and
fed-batch) under substrate limited condition. In
consequence FeedBeads can increase the probability to
identify an optimal production strain during the
screening phase.
advantages:
- new screening
possibilities - increase the probability to find an
optimal production strain - no investment costs (no
pumps) - suitable for high through put
screening(HTS) - easy application
FeedBeads for shake
flasks:
For the application of FeedBeads in
shake flasks small polymer discs are produced. The
production method ensures defined composition and
substrate (e.g. glucose) release of FeedBeads.
FeadsBeads are delivered steril and can therefore be
easily transferred into shaken bioreactors under the
cleanbench. Especially for substrate inhibited and
catabolite repressed biological systems the application
of FeedBeads can result in very important new
information during the screening phase.
Feedbeads for microtiter
plates:
FeedBeads are attached to the bottom
of each well of the microtiter plate. The production
method ensures defined composition and substrate (e.g.
glucose) release of FeedBeads. As the microtiter plates
(2.2 mL deep well) are standardised the FeedBead-MTP can
easily br integrated in existing equipment. The
FeedBead-MTP is shipped steril with a cover.
FeedBeads were developed from the following
partners: Supported by DBU (Deutschen Bundesstiftung
Umwelt (Osnabrück))